Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-κB-dependent Mechanism of Action of Melatonin

The advent of combination therapy unprecedentedly shifted the paradigm of cancer treatment by reconstructing the conventional protocols. By identifying the anti-tumoral activity for different natural products, recent interest has focused on inventing the combined-modality strategies in order to increase the cure rates of cancer, while reducing the toxic side effects of current intensive regimen...

Evaluation of Cytotoxicity Effects of Combination Nano-Curcumin and Berberine in Breast Cancer Cell Line

Background: Berberine and Nano-curcumin are two herbal medicines with strong anti-cancer effects on tumor cells, but low toxicity on normal cells, when used alone. Breast cancer is known as the most common cancer in women and second deadly one. In this study, we evaluated the cytotoxicity effects of combination Berberine and Nano-curcumin in breast cancer cell line to see whether they have furt...

Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism

Human exposure to inorganic arsenic leads to various dermal disorders, including hyperkeratosis and skin cancer. Curcumin is demonstrated to induce remarkable antioxidant activity in a variety of cells and tissues. The present study aimed at identifying curcumin as a potent activator of nuclear factor erythroid 2-related factor 2 (NRF2) and demonstrating its protective effect against inorganic ...

Curcumin Interferes with HER-2 Signaling in a Redox-Dependent Manner in SK-BR-3 Human Breast Cancer Cells

Cite this article: Venkiteswaran S, Hsu HC, Yang PA, Thomas T, Thomas TJ (2014) Curcumin Interferes with HER-2 Signaling in a Redox-Dependent Manner in SK-BR-3 Human Breast Cancer Cells. J Hum Nutr Food Sci 2(2): 1030. *Corresponding author Thomas TJ, Departments of Medicine, Environmental and Occupational Medicine, Rutgers Robert Wood Johnson Medical School and Rutgers Cancer Institute of New ...

Cytotoxicity against Breast Cancer Cells NK Cell Antibody-Dependent Cellular Fc-Optimized NKG2D-Fc Constructs Induce